Assessing drug-induced dyskinesia in the clinic, the laboratory and the natural environment of patients.
Identifieur interne : 001720 ( Main/Exploration ); précédent : 001719; suivant : 001721Assessing drug-induced dyskinesia in the clinic, the laboratory and the natural environment of patients.
Auteurs : Benoit Carignan [Canada] ; Jean-François Daneault ; Christian DuvalSource :
- Journal of Parkinson's disease [ 1877-718X ] ; 2011.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Antiparkinson Agents.
- diagnosis : Dyskinesia, Drug-Induced.
- drug therapy : Parkinson Disease.
- physiopathology : Dyskinesia, Drug-Induced.
- psychology : Dyskinesia, Drug-Induced.
- Humans, Medical Laboratory Personnel, Quality of Life.
Abstract
The assessment of drug-induced dyskinesia (DID) in Parkinson's disease represents a formidable challenge for clinicians and researchers alike. The present review describes the current assessment tools used in the clinic, where different scales have been developed for monitoring levels of DID in patients. We also review laboratory tools used to assess the quantity and characteristics of DID. Finally, we review assessment methods currently in development for monitoring DID and voluntary mobility in the natural living environment of patients. Here, we discuss the strengths and weaknesses of these tools as it pertains to their efficacy in assessing the quantity of DID, its characteristics, as well as its impact on the quality of life of patients. Finally, we discuss ongoing challenges and research questions that may guide future development of assessment methods aimed at monitoring DID and its impact on daily lives of patients.
DOI: 10.3233/JPD-2011-11054
PubMed: 23939342
Affiliations:
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Le document en format XML
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<author><name sortKey="Daneault, Jean Francois" sort="Daneault, Jean Francois" uniqKey="Daneault J" first="Jean-François" last="Daneault">Jean-François Daneault</name>
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<term>Parkinson Disease (drug therapy)</term>
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<front><div type="abstract" xml:lang="en">The assessment of drug-induced dyskinesia (DID) in Parkinson's disease represents a formidable challenge for clinicians and researchers alike. The present review describes the current assessment tools used in the clinic, where different scales have been developed for monitoring levels of DID in patients. We also review laboratory tools used to assess the quantity and characteristics of DID. Finally, we review assessment methods currently in development for monitoring DID and voluntary mobility in the natural living environment of patients. Here, we discuss the strengths and weaknesses of these tools as it pertains to their efficacy in assessing the quantity of DID, its characteristics, as well as its impact on the quality of life of patients. Finally, we discuss ongoing challenges and research questions that may guide future development of assessment methods aimed at monitoring DID and its impact on daily lives of patients.</div>
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<country name="Canada"><region name="Québec"><name sortKey="Carignan, Benoit" sort="Carignan, Benoit" uniqKey="Carignan B" first="Benoit" last="Carignan">Benoit Carignan</name>
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